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Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Yates, Lucy R; Gerstung, Moritz; Knappskog, Stian; Desmedt, Christine; Gundem, Gunes; Van Loo, Peter; Aas, Turid; Alexandrov, Ludmil B; Larsimont, Denis; Davies, Helen; Li, Yilong; Ju, Young Seok; Ramakrishna, Manasa; Haugland, Hans Kristian; Lilleng, Peer Kaare; Nik-Zainal, Serena; McLaren, Stuart; Butler, Adam; Martin, Sancha; Glodzik, Dominic; Menzies, Andrew; Raine, Keiran; Hinton, Jonathan; Jones, David; Mudie, Laura J; Jiang, Bing; Vincent, Delphine; Greene-Colozzi, April; Adnet, Pierre-Yves; Fatima, Aquila; Maetens, Marion; Ignatiadis, Michail; Stratton, Michael R; Sotiriou, Christos; Richardson, Andrea L; Lønning, Per Eystein; Wedge, David C; Campbell, Peter J.
Affiliation
  • Yates LR; 1] Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. [2] Department of Oncology, The University of Cambridge, Cambridge, UK.
  • Gerstung M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Knappskog S; 1] Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway. [2] Department of Oncology, Haukeland University Hospital, Bergen, Norway.
  • Desmedt C; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Gundem G; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Van Loo P; 1] Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. [2] Department of Human Genetics, University of Leuven, Leuven, Belgium.
  • Aas T; Department of Surgery, Haukeland University Hospital, Bergen, Norway.
  • Alexandrov LB; 1] Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. [2] Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
  • Larsimont D; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Davies H; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Li Y; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Ju YS; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Ramakrishna M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Haugland HK; Department of Pathology, Haukeland University Hospital, Bergen, Norway.
  • Lilleng PK; 1] Department of Pathology, Haukeland University Hospital, Bergen, Norway. [2] The Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Nik-Zainal S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • McLaren S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Butler A; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Martin S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Glodzik D; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Menzies A; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Raine K; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Hinton J; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Jones D; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Mudie LJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Jiang B; Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Vincent D; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Greene-Colozzi A; Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Adnet PY; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Fatima A; Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Maetens M; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Ignatiadis M; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Stratton MR; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Sotiriou C; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Richardson AL; 1] Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Lønning PE; 1] Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway. [2] Department of Oncology, Haukeland University Hospital, Bergen, Norway.
  • Wedge DC; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Campbell PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
Nat Med ; 21(7): 751-9, 2015 Jul.
Article in En | MEDLINE | ID: mdl-26099045
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Breast Neoplasms / High-Throughput Nucleotide Sequencing Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Breast Neoplasms / High-Throughput Nucleotide Sequencing Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos