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Lysosome targeting fluorescence probe for imaging intracellular thiols.
Kand, Dnyaneshwar; Saha, Tanmoy; Lahiri, Mayurika; Talukdar, Pinaki.
Affiliation
  • Kand D; Department of Chemistry, Indian Institute of Science Education and Research Pune, Pune 411008, India. ptalukdar@iiserpune.ac.in.
Org Biomol Chem ; 13(30): 8163-8, 2015 Aug 14.
Article in En | MEDLINE | ID: mdl-26140677
A BODIPY-based fluorescence turn-on probe, exhibiting high selectivity and sensitivity towards intracellular thiols with excellent lysosomal localization is reported. The probe displayed fast response towards biothiols in aqueous solution. Localization of the probe in lysosome was demonstrated by intracellular colocalization studies with the aid of LysoSensor Green.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfhydryl Compounds / Imaging, Three-Dimensional / Intracellular Space / Fluorescent Dyes / Lysosomes Limits: Humans Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Affiliation country: India Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfhydryl Compounds / Imaging, Three-Dimensional / Intracellular Space / Fluorescent Dyes / Lysosomes Limits: Humans Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Affiliation country: India Country of publication: Reino Unido