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Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells.
Ku, Jin Mo; Kim, Soon Re; Hong, Se Hyang; Choi, Han-Seok; Seo, Hye Sook; Shin, Yong Cheol; Ko, Seong-Gyu.
Affiliation
  • Ku JM; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea.
  • Kim SR; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea.
  • Hong SH; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea.
  • Choi HS; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea.
  • Seo HS; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea.
  • Shin YC; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea.
  • Ko SG; Laboratory of Clinical Biology and Pharmacogenomics, Department of Preventive Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, 130-701, Republic of Korea. epiko@khu.ac.kr.
Mol Cell Biochem ; 409(1-2): 33-43, 2015 Nov.
Article in En | MEDLINE | ID: mdl-26169986
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Breast Neoplasms / Doxorubicin / NF-kappa B / Apoptosis / STAT3 Transcription Factor / G2 Phase Cell Cycle Checkpoints Limits: Female / Humans Language: En Journal: Mol Cell Biochem Year: 2015 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Breast Neoplasms / Doxorubicin / NF-kappa B / Apoptosis / STAT3 Transcription Factor / G2 Phase Cell Cycle Checkpoints Limits: Female / Humans Language: En Journal: Mol Cell Biochem Year: 2015 Document type: Article