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Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).
Zheng, Jie; van de Veerdonk, Frank L; Crossland, Katherine L; Smeekens, Sanne P; Chan, Chun M; Al Shehri, Tariq; Abinun, Mario; Gennery, Andrew R; Mann, Jelena; Lendrem, Dennis W; Netea, Mihai G; Rowan, Andrew D; Lilic, Desa.
Affiliation
  • Zheng J; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • van de Veerdonk FL; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
  • Crossland KL; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Smeekens SP; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
  • Chan CM; Musculoskeletal Research Group, Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Al Shehri T; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Abinun M; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Gennery AR; Department of Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, UK.
  • Mann J; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Lendrem DW; Department of Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, UK.
  • Netea MG; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Rowan AD; Musculoskeletal Research Group, Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Lilic D; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
Eur J Immunol ; 45(10): 2834-46, 2015 Oct.
Article in En | MEDLINE | ID: mdl-26255980
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Candidiasis, Chronic Mucocutaneous / Gene Expression Regulation / STAT1 Transcription Factor / STAT3 Transcription Factor / Mutation Limits: Female / Humans / Male Language: En Journal: Eur J Immunol Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Alemania
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Candidiasis, Chronic Mucocutaneous / Gene Expression Regulation / STAT1 Transcription Factor / STAT3 Transcription Factor / Mutation Limits: Female / Humans / Male Language: En Journal: Eur J Immunol Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Alemania