Discovery of 4-arylamido 3-methyl isoxazole derivatives as novel FMS kinase inhibitors.

Im, Daseul; Jung, Kyungjin; Yang, Songyi; Aman, Waqar; Hah, Jung-Mi

Im, Daseul; Jung, Kyungjin; Yang, Songyi; Aman, Waqar; Hah, Jung-Mi.

Affiliation

Im D; Department of Pharmacy, College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do, 426-791, Republic of Korea.
Jung K; Department of Pharmacy, College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do, 426-791, Republic of Korea.
Yang S; Department of Pharmacy, College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do, 426-791, Republic of Korea.
Aman W; Department of Pharmacy, College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do, 426-791, Republic of Korea.
Hah JM; Department of Pharmacy, College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do, 426-791, Republic of Korea. Electronic address: jhah@hanyang.ac.kr.

Eur J Med Chem ; 102: 600-10, 2015 Sep 18.

Article in En | MEDLINE | ID: mdl-26318067

Subject(s)
Key words

4-arylamido 3-methyl isoxazoles; Antiproliferative activity; Hematopoietic cell line; Kinase inhibitor; Kinase selectivity

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Protein Kinase Inhibitors / Drug Discovery / Isoxazoles Limits: Humans Language: En Journal: Eur J Med Chem Year: 2015 Document type: Article Country of publication: Francia

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google