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Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability.
Gordon, Laurie J; Allen, Morven; Artursson, Per; Hann, Michael M; Leavens, Bill J; Mateus, André; Readshaw, Simon; Valko, Klara; Wayne, Gareth J; West, Andy.
Affiliation
  • Gordon LJ; Department of Biological Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Allen M; Department of Biological Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Artursson P; Department of Pharmacy, Uppsala University, Uppsala, Sweden Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP) at Chemical Biology Consortium, Uppsala, Sweden.
  • Hann MM; Department of Chemical Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Leavens BJ; Department of Chemical Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Mateus A; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Readshaw S; Department of Chemical Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Valko K; Department of Chemical Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • Wayne GJ; Department of Target and Pathway Validation, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK.
  • West A; Department of Chemical Sciences, Molecular Discovery Research, GlaxoSmithKline, Stevenage, UK Andy.West@gsk.com.
J Biomol Screen ; 21(2): 156-64, 2016 Feb.
Article in En | MEDLINE | ID: mdl-26336900
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations Limits: Humans Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations Limits: Humans Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos