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P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.
Skowronska-Krawczyk, Dorota; Zhao, Ling; Zhu, Jie; Weinreb, Robert N; Cao, Guiqun; Luo, Jing; Flagg, Ken; Patel, Sherrina; Wen, Cindy; Krupa, Martin; Luo, Hongrong; Ouyang, Hong; Lin, Danni; Wang, Wenqiu; Li, Gen; Xu, Yanxin; Li, Oulan; Chung, Christopher; Yeh, Emily; Jafari, Maryam; Ai, Michael; Zhong, Zheng; Shi, William; Zheng, Lianghong; Krawczyk, Michal; Chen, Daniel; Shi, Catherine; Zin, Carolyn; Zhu, Jin; Mellon, Pamela L; Gao, Weiwei; Abagyan, Ruben; Zhang, Liangfang; Sun, Xiaodong; Zhong, Sheng; Zhuo, Yehong; Rosenfeld, Michael G; Liu, Yizhi; Zhang, Kang.
Affiliation
  • Skowronska-Krawczyk D; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhao L; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
  • Zhu J; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
  • Weinreb RN; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Cao G; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan 610041, China.
  • Luo J; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Flagg K; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Patel S; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Wen C; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Krupa M; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Luo H; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ouyang H; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
  • Lin D; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Wang W; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Ophthalmology, Shanghai First People's Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai 20080, China.
  • Li G; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan 610041, China.
  • Xu Y; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan 610041, China.
  • Li O; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Sichuan 610041, China; Guangzhou KangRui Biological Pharmaceutical Technology Company Ltd., Guangzhou 510005, China.
  • Chung C; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Yeh E; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Jafari M; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ai M; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhong Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
  • Shi W; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zheng L; Guangzhou KangRui Biological Pharmaceutical Technology Company Ltd., Guangzhou 510005, China.
  • Krawczyk M; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Chen D; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Shi C; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zin C; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhu J; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Mellon PL; Department of Reproductive Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gao W; Department of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Abagyan R; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhang L; Department of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Sun X; Department of Ophthalmology, Shanghai First People's Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai 20080, China.
  • Zhong S; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhuo Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
  • Rosenfeld MG; Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Liu Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China. Electronic address: yzliu62@yahoo.com.
  • Zhang K; Shiley Eye Institute, Department of Ophthalmology and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China; Molecular Medicine Research C
Mol Cell ; 59(6): 931-40, 2015 Sep 17.
Article in En | MEDLINE | ID: mdl-26365380
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Ganglion Cells / Trans-Activators / Glaucoma, Open-Angle / Homeodomain Proteins / Cyclin-Dependent Kinase Inhibitor p16 Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Ganglion Cells / Trans-Activators / Glaucoma, Open-Angle / Homeodomain Proteins / Cyclin-Dependent Kinase Inhibitor p16 Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos