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N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.
Jin, Niyun; Wang, Yang; Crawford, Frances; White, Janice; Marrack, Philippa; Dai, Shaodong; Kappler, John W.
Affiliation
  • Jin N; Howard Hughes Medical Institute, Denver, CO 80206; Department of Biomedical Research, National Jewish Health, Denver, CO 80206; Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO 80045;
  • Wang Y; Department of Biomedical Research, National Jewish Health, Denver, CO 80206;
  • Crawford F; Howard Hughes Medical Institute, Denver, CO 80206; Department of Biomedical Research, National Jewish Health, Denver, CO 80206;
  • White J; Department of Biomedical Research, National Jewish Health, Denver, CO 80206;
  • Marrack P; Howard Hughes Medical Institute, Denver, CO 80206; Department of Biomedical Research, National Jewish Health, Denver, CO 80206; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045;
  • Dai S; Department of Biomedical Research, National Jewish Health, Denver, CO 80206; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045; dais@njhealth.org kapplerj@njhealth.org.
  • Kappler JW; Howard Hughes Medical Institute, Denver, CO 80206; Department of Biomedical Research, National Jewish Health, Denver, CO 80206; Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO 80045; Department of Immunology and Microbiology, University of Colorado School of Medicine,
Proc Natl Acad Sci U S A ; 112(43): 13318-23, 2015 Oct 27.
Article in En | MEDLINE | ID: mdl-26453556
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Autoantigens / Models, Molecular / Diabetes Mellitus, Type 1 / Chromogranin A / Epitopes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Autoantigens / Models, Molecular / Diabetes Mellitus, Type 1 / Chromogranin A / Epitopes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Document type: Article Country of publication: Estados Unidos