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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.
Zhang, Lin; Zhang, Siyuan; Yao, Jun; Lowery, Frank J; Zhang, Qingling; Huang, Wen-Chien; Li, Ping; Li, Min; Wang, Xiao; Zhang, Chenyu; Wang, Hai; Ellis, Kenneth; Cheerathodi, Mujeeburahiman; McCarty, Joseph H; Palmieri, Diane; Saunus, Jodi; Lakhani, Sunil; Huang, Suyun; Sahin, Aysegul A; Aldape, Kenneth D; Steeg, Patricia S; Yu, Dihua.
Affiliation
  • Zhang L; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Zhang S; Cancer Biology Program, Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
  • Yao J; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Lowery FJ; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
  • Zhang Q; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Huang WC; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Li P; Cancer Biology Program, Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
  • Li M; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Wang X; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Zhang C; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Wang H; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Ellis K; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Cheerathodi M; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • McCarty JH; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Palmieri D; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center.
  • Saunus J; Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  • Lakhani S; Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  • Huang S; Woman's Malignancies Branch, National Cancer Institute, Bethesda, MD 20892, USA.
  • Sahin AA; University of Queensland Centre for Clinical Research, Herston, QLD 4029, AUS.
  • Aldape KD; University of Queensland Centre for Clinical Research, Herston, QLD 4029, AUS.
  • Steeg PS; Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  • Yu D; Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
Nature ; 527(7576): 100-104, 2015 Nov 05.
Article in En | MEDLINE | ID: mdl-26479035
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Gene Expression Regulation, Neoplastic / Gene Silencing / MicroRNAs / PTEN Phosphohydrolase / Exosomes / Tumor Microenvironment Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2015 Document type: Article Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Gene Expression Regulation, Neoplastic / Gene Silencing / MicroRNAs / PTEN Phosphohydrolase / Exosomes / Tumor Microenvironment Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2015 Document type: Article Country of publication: Reino Unido