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Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity.
Dyer, Paul D R; Shepherd, Thomas R; Gollings, Alexander S; Shorter, Susan A; Gorringe-Pattrick, Monique A M; Tang, Chun-Kit; Cattoz, Beatrice N; Baillie, Les; Griffiths, Peter C; Richardson, Simon C W.
Affiliation
  • Dyer PDR; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Shepherd TR; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Gollings AS; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Shorter SA; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Gorringe-Pattrick MAM; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Tang CK; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Cattoz BN; Department of Pharmaceutical, Chemical and Environmental Science, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.
  • Baillie L; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF10 3AX, UK.
  • Griffiths PC; Department of Pharmaceutical, Chemical and Environmental Science, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.
  • Richardson SCW; Intercellular Delivery Solutions Laboratory, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK. Electronic address: S.C.W.Richardson@Greenwich.ac.uk.
J Control Release ; 220(Pt A): 316-328, 2015 Dec 28.
Article in En | MEDLINE | ID: mdl-26546271
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Transfection / Oligonucleotides, Antisense / RNA, Small Interfering / RNA Interference / Gene Knockdown Techniques / Antigens, Bacterial Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Países Bajos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Transfection / Oligonucleotides, Antisense / RNA, Small Interfering / RNA Interference / Gene Knockdown Techniques / Antigens, Bacterial Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Países Bajos