Mutations in the transcriptional repressor REST predispose to Wilms tumor.

Mahamdallie, Shazia S; Hanks, Sandra; Karlin, Kristen L; Zachariou, Anna; Perdeaux, Elizabeth R; Ruark, Elise; Shaw, Chad A; Renwick, Alexander; Ramsay, Emma; Yost, Shawn; Elliott, Anna; Birch, Jillian; Capra, Michael; Gray, Juliet; Hale, Juliet; Kingston, Judith; Levitt, Gill; McLean, Thomas; Sheridan, Eamonn; Renwick, Anthony; Seal, Sheila; Stiller, Charles; Sebire, Neil; Westbrook, Thomas F; Rahman, Nazneen

Mahamdallie, Shazia S; Hanks, Sandra; Karlin, Kristen L; Zachariou, Anna; Perdeaux, Elizabeth R; Ruark, Elise; Shaw, Chad A; Renwick, Alexander; Ramsay, Emma; Yost, Shawn; Elliott, Anna; Birch, Jillian; Capra, Michael; Gray, Juliet; Hale, Juliet; Kingston, Judith; Levitt, Gill; McLean, Thomas; Sheridan, Eamonn; Renwick, Anthony; Seal, Sheila; Stiller, Charles; Sebire, Neil; Westbrook, Thomas F; Rahman, Nazneen.

Affiliation

Mahamdallie SS; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Hanks S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Karlin KL; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA.
Zachariou A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.
Perdeaux ER; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Ruark E; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Shaw CA; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Renwick A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.
Ramsay E; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.
Yost S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Elliott A; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Birch J; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Capra M; Paediatric and Familial Cancer Research Group, University of Manchester, Manchester, UK.
Gray J; Haematology Oncology-National Paediatric Centre, Our Lady's Children's Hospital, Dublin, Ireland.
Hale J; Cancer Sciences Unit, University of Southampton, Southampton, UK.
Kingston J; Department of Paediatric and Adolescent Haematology and Oncology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK.
Levitt G; Department of Haematology and Oncology, Great Ormond Street Hospital, London, UK.
McLean T; Department of Haematology and Oncology, Great Ormond Street Hospital, London, UK.
Sheridan E; Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Renwick A; Yorkshire Clinical Genetics Service, Chapel Allerton Hospital, Leeds, UK.
Seal S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Stiller C; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Sebire N; Public Health England, Oxford, UK.
Westbrook TF; Department of Histopathology and Paediatric Laboratory Medicine, Great Ormond Street Hospital, London, UK.
Rahman N; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA.

Nat Genet ; 47(12): 1471-4, 2015 Dec.

Article in En | MEDLINE | ID: mdl-26551668

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Genetic Markers / Gene Expression Regulation / Wilms Tumor / Genetic Predisposition to Disease / Kidney Neoplasms / Mutation Type of study: Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2015 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos

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