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Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4.
Kil, Kun-Eek; Poutiainen, Pekka; Zhang, Zhaoda; Zhu, Aijun; Kuruppu, Darshini; Prabhakar, Shilpa; Choi, Ji-Kyung; Tannous, Bakhos A; Brownell, Anna-Liisa.
Affiliation
  • Kil KE; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149, 13th St., Suite 2301, Charlestown, MA 02129, USA.
  • Poutiainen P; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149, 13th St., Suite 2301, Charlestown, MA 02129, USA.
  • Zhang Z; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149, 13th St., Suite 2301, Charlestown, MA 02129, USA.
  • Zhu A; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149, 13th St., Suite 2301, Charlestown, MA 02129, USA.
  • Kuruppu D; Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Prabhakar S; Experimental Therapeutics and Molecular Imaging Laboratory, Department of Neurology, Neuroscience Center, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Choi JK; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149, 13th St., Suite 2301, Charlestown, MA 02129, USA.
  • Tannous BA; Experimental Therapeutics and Molecular Imaging Laboratory, Department of Neurology, Neuroscience Center, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Brownell AL; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149, 13th St., Suite 2301, Charlestown, MA 02129, USA. Electronic address: abrownell@mgh.harvard.edu.
Bioorg Med Chem Lett ; 26(1): 133-9, 2016 Jan 01.
Article in En | MEDLINE | ID: mdl-26602273
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Picolinic Acids / Radioligand Assay / Thiophenes / Receptors, Metabotropic Glutamate / Radiopharmaceuticals / Positron-Emission Tomography Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Picolinic Acids / Radioligand Assay / Thiophenes / Receptors, Metabotropic Glutamate / Radiopharmaceuticals / Positron-Emission Tomography Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido