One-year results of needle fasciotomy and collagenase injection in treatment of Dupuytren's contracture: A two-centre prospective randomized clinical trial.
J Hand Surg Eur Vol
; 41(6): 577-82, 2016 Jul.
Article
in En
| MEDLINE
| ID: mdl-26631343
ABSTRACT
UNLABELLED The objective of this study was to compare early and 1 year outcome of needle fasciotomy and collagenase injection for Dupuytren's disease. Inclusion criteria were primary Dupuytren's contracture excluding the thumb with a palpable cord and a total extension deficit, i.e. a fixed flexion from 30° to 135° with less than 60° in the proximal interphalangeal joint. The most affected ray was randomized to either treatment at two centres. Passive extension deficits for each joint before and after treatment, and at 3 and 12 months, were recorded together with complications. A total of 96 rays in 93 patients were included. The average total extension deficits before treatment were 60° or more in both groups, and were largely made up of contractures at the metacarpophalangeal joints. The deficits were reduced by 75% in both groups at 3 months and by 70% in both groups at 12 months. Four patients in the needle fasciotomy group and eight patients in the collagenase group had skin ruptures. At 3 months and 1 year, the outcomes of needle fasciotomy and collagenase injection are the same in Dupuytren's disease with predominantly metacarpophalangeal joint involvement. LEVEL OF EVIDENCE 2.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Collagenases
/
Dupuytren Contracture
/
Finger Joint
/
Fasciotomy
/
Metacarpophalangeal Joint
/
Needles
Type of study:
Clinical_trials
/
Observational_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Hand Surg Eur Vol
Year:
2016
Document type:
Article
Affiliation country:
Suecia