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Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5.
Hunt, Lilian E; Noyvert, Boris; Bhaw-Rosun, Leena; Sesay, Abdul K; Paternoster, Lavinia; Nohr, Ellen A; Davey Smith, George; Tommerup, Niels; Sørensen, Thorkild I A; Elgar, Greg.
Affiliation
  • Hunt LE; The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, Mill Hill, London, NW7 1AA, UK.
  • Noyvert B; The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, Mill Hill, London, NW7 1AA, UK.
  • Bhaw-Rosun L; Genomics Facility, The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, Mill Hill, London, NW7 1AA, UK.
  • Sesay AK; Genomics Facility, The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, Mill Hill, London, NW7 1AA, UK.
  • Paternoster L; MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, University of Bristol, Bristol, UK.
  • Nohr EA; Research Unit for Gynecology and Obstetrics, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
  • Davey Smith G; MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, University of Bristol, Bristol, UK.
  • Tommerup N; Willhelm Johannsen Centre for Functional Genome Research, Department of Cellular and Molecular Medicine, The Faculty of Health Sciences, The University of Copenhagen, Blegdamsvej 3B, DK-2200, Copenhagen N, Denmark.
  • Sørensen TI; MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, University of Bristol, Bristol, UK.
  • Elgar G; The Novo Nordisk Foundation Centre for Basic Metabolic Research, Section on Metabolic genetics, The Faculty of Health and Medical Sciences, University of Copenhagen, DK2100, Copenhagen Ø, Denmark.
Genome Med ; 7: 126, 2015 Dec 07.
Article in En | MEDLINE | ID: mdl-26642925
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Proteins / Homeodomain Proteins / Genetic Loci / Obesity Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Genome Med Year: 2015 Document type: Article Affiliation country: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Proteins / Homeodomain Proteins / Genetic Loci / Obesity Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Genome Med Year: 2015 Document type: Article Affiliation country: Reino Unido