Your browser doesn't support javascript.
loading
Mucosal IgG Levels Correlate Better with Respiratory Syncytial Virus Load and Inflammation than Plasma IgG Levels.
Vissers, Marloes; Ahout, Inge M L; de Jonge, Marien I; Ferwerda, Gerben.
Affiliation
  • Vissers M; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Ahout IM; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • de Jonge MI; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Ferwerda G; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands Gerben.Ferwerda@radboudumc.nl.
Clin Vaccine Immunol ; 23(3): 243-5, 2015 Dec 09.
Article in En | MEDLINE | ID: mdl-26656116
ABSTRACT
Maternal vaccination is currently considered a strategy against respiratory syncytial virus (RSV) infections. In RSV-infected infants, high mucosal IgG levels correlated better with reduced RSV load and lower mucosal CXCL10 levels than plasma IgG levels. For future vaccination strategies against RSV, more focus should be on the mucosal humoral immune response.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Immunity, Mucosal / Chemokine CXCL10 / Immunity, Maternally-Acquired / Antibodies, Viral Limits: Female / Humans / Infant / Male Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2015 Document type: Article Affiliation country: Países Bajos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Immunity, Mucosal / Chemokine CXCL10 / Immunity, Maternally-Acquired / Antibodies, Viral Limits: Female / Humans / Infant / Male Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2015 Document type: Article Affiliation country: Países Bajos