Centrifugal enhancement of human immunodeficiency virus (HIV) and human herpesvirus type 6 (HHV-6) infection in vitro.
J Virol Methods
; 24(1-2): 85-90, 1989.
Article
in En
| MEDLINE
| ID: mdl-2668317
ABSTRACT
The effect of centrifugal inoculation of human immunodeficiency virus (HIV) and human herpesvirus-6 (HHV-6) on the infectivity of the viruses for cell cultures was examined. Three HIV-1 strains, ARV-2, HTLV-IIIb and a local isolate, WA-46c, were tested in peripheral blood lymphocytes, HUT-78, H9 and MT-2 cells. The HHV-6 strain was a local isolate and was studied only in peripheral blood lymphocyte cultures. Centrifugal inoculation of the viruses at a force of 2500 x g for 60 min, enhanced HIV-1 infectivity by a factor of about 10-fold in all cell cultures tested. Infectivity was increased about 100-fold for HHV-6.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Virology
/
HIV
/
Herpesviridae
Limits:
Humans
Language:
En
Journal:
J Virol Methods
Year:
1989
Document type:
Article
Affiliation country:
Australia