Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.
Osteoarthritis Cartilage
; 24(5): 892-901, 2016 May.
Article
in En
| MEDLINE
| ID: mdl-26687824
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Repressor Proteins
/
Trans-Activators
/
Adenosine Triphosphate
/
Chondrocytes
/
Calcium Signaling
/
Mechanotransduction, Cellular
Limits:
Animals
/
Humans
/
Male
Language:
En
Journal:
Osteoarthritis Cartilage
Journal subject:
ORTOPEDIA
/
REUMATOLOGIA
Year:
2016
Document type:
Article
Country of publication:
Reino Unido