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Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease.
Lemes, Laís Flávia Nunes; de Andrade Ramos, Giselle; de Oliveira, Andressa Souza; da Silva, Fernanda Motta R; de Castro Couto, Gina; da Silva Boni, Marina; Guimarães, Marcos Jorge R; Souza, Isis Nem O; Bartolini, Manuela; Andrisano, Vincenza; do Nascimento Nogueira, Patrícia Coelho; Silveira, Edilberto Rocha; Brand, Guilherme D; Soukup, Ondrej; Korábecný, Jan; Romeiro, Nelilma C; Castro, Newton G; Bolognesi, Maria Laura; Romeiro, Luiz Antonio Soares.
Affiliation
  • Lemes LFN; Department of Pharmacy, Health Sciences Faculty, University of Brasília, Campus Universitário Darcy Ribeiro, 70910-900, Brasília, DF, Brazil; LADETER, Catholic University of Brasília, QS 07, Lote 01, EPCT, Águas Claras, 71966-700, Brasília, DF, Brazil.
  • de Andrade Ramos G; Department of Pharmacy, Health Sciences Faculty, University of Brasília, Campus Universitário Darcy Ribeiro, 70910-900, Brasília, DF, Brazil; LADETER, Catholic University of Brasília, QS 07, Lote 01, EPCT, Águas Claras, 71966-700, Brasília, DF, Brazil.
  • de Oliveira AS; Department of Pharmacy, Health Sciences Faculty, University of Brasília, Campus Universitário Darcy Ribeiro, 70910-900, Brasília, DF, Brazil; LADETER, Catholic University of Brasília, QS 07, Lote 01, EPCT, Águas Claras, 71966-700, Brasília, DF, Brazil.
  • da Silva FMR; Biomedical Sciences Institute (ICB), Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
  • de Castro Couto G; Biomedical Sciences Institute (ICB), Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
  • da Silva Boni M; Biomedical Sciences Institute (ICB), Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
  • Guimarães MJR; Biomedical Sciences Institute (ICB), Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
  • Souza INO; Biomedical Sciences Institute (ICB), Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
  • Bartolini M; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.
  • Andrisano V; Department for Life Quality Studies, University of Bologna, Corso D'Augusto 237, 47921, Rimini, Italy.
  • do Nascimento Nogueira PC; CENAUREMN, Department of Organic and Inorganic Chemistry, Federal University of Ceará, 60021-970, Fortaleza, CE, Brazil.
  • Silveira ER; CENAUREMN, Department of Organic and Inorganic Chemistry, Federal University of Ceará, 60021-970, Fortaleza, CE, Brazil.
  • Brand GD; Chemistry Institute, University of Brasília, Campus Universitário Darcy Ribeiro, 70910-900, Brasília, DF, Brazil.
  • Soukup O; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; National Institute of Mental Health, Topolová 748, 250 67, Klecany, Czech Republic.
  • Korábecný J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; National Institute of Mental Health, Topolová 748, 250 67, Klecany, Czech Republic.
  • Romeiro NC; LICC - Laboratório Integrado de Computação Científica, NUPEM, Federal University of Rio de Janeiro, 27901-000, Macaé, RJ, Brazil.
  • Castro NG; Biomedical Sciences Institute (ICB), Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, Brazil.
  • Bolognesi ML; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy. Electronic address: marialaura.bolognesi@unibo.it.
  • Romeiro LAS; Department of Pharmacy, Health Sciences Faculty, University of Brasília, Campus Universitário Darcy Ribeiro, 70910-900, Brasília, DF, Brazil; LADETER, Catholic University of Brasília, QS 07, Lote 01, EPCT, Águas Claras, 71966-700, Brasília, DF, Brazil. Electronic address: luizromeiro@unb.br.
Eur J Med Chem ; 108: 687-700, 2016 Jan 27.
Article in En | MEDLINE | ID: mdl-26735910
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Cholinesterase Inhibitors / Cholinesterases / Alzheimer Disease Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2016 Document type: Article Affiliation country: Brasil Country of publication: Francia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Cholinesterase Inhibitors / Cholinesterases / Alzheimer Disease Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2016 Document type: Article Affiliation country: Brasil Country of publication: Francia