Doing more with less: New markers for sarcoma diagnosis and their applicability to cytology specimens.
Diagn Cytopathol
; 44(4): 351-60, 2016 Apr.
Article
in En
| MEDLINE
| ID: mdl-26780171
ABSTRACT
Sarcomas are a rare and extremely diverse set of neoplasms that are often a challenge to diagnose for pathologists. For a number of reasons, primary diagnosis of soft tissue neoplasms is increasingly being performed on small biopsy specimens including fine needle aspiration (FNA) and core needle biopsy (CNB). In the last several years, there has been a significant increase in our understanding of the molecular pathogenesis of this group of tumors. New insights into the genetic mechanisms of tumor formation have been exploited to create a new generation of diagnostic markers that are accessible to most laboratories. This review describes a number of new ancillary markers, and how they can facilitate accurate diagnosis of soft tissue neoplasms on FNA/CNB.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoma
/
Soft Tissue Neoplasms
/
Biomarkers, Tumor
Type of study:
Diagnostic_studies
Limits:
Adult
/
Humans
Language:
En
Journal:
Diagn Cytopathol
Journal subject:
PATOLOGIA
Year:
2016
Document type:
Article