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5-Benzylidene-hydantoin is a new scaffold for SIRT inhibition: From virtual screening to activity assays.
Sacconnay, Lionel; Ryckewaert, Lucie; Randazzo, Giuseppe Marco; Petit, Charlotte; Passos, Carolina Dos Santos; Jachno, Jelena; Michailoviene, Vilma; Zubriene, Asta; Matulis, Daumantas; Carrupt, Pierre-Alain; Simões-Pires, Claudia Avello; Nurisso, Alessandra.
Affiliation
  • Sacconnay L; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
  • Ryckewaert L; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
  • Randazzo GM; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
  • Petit C; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
  • Passos Cdos S; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
  • Jachno J; Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, LT-02241 Vilnius, Lithuania.
  • Michailoviene V; Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, LT-02241 Vilnius, Lithuania.
  • Zubriene A; Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, LT-02241 Vilnius, Lithuania.
  • Matulis D; Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, LT-02241 Vilnius, Lithuania.
  • Carrupt PA; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland.
  • Simões-Pires CA; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland. Electronic address: claudia.avello@unige.ch.
  • Nurisso A; School of Pharmaceutical Sciences, University of Geneva-University of Lausanne, 30 quai E. Ansermet, CH-1211 Geneva 4, Switzerland. Electronic address: alessandra.nurisso@unige.ch.
Eur J Pharm Sci ; 85: 59-67, 2016 Mar 31.
Article in En | MEDLINE | ID: mdl-26791955
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzylidene Compounds / Sirtuins / Hydantoins Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2016 Document type: Article Affiliation country: Suiza
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzylidene Compounds / Sirtuins / Hydantoins Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2016 Document type: Article Affiliation country: Suiza