HYPERGLYCAEMIC HEMIBALLISMUS: IMPLICATIONS FROM CONNECTIVITY ANALYSIS FOR COGNITIVE IMPAIRMENTS.
Ideggyogy Sz
; 68(11-12): 417-21, 2015 Nov 30.
Article
in En
| MEDLINE
| ID: mdl-26821516
ABSTRACT
Hyperglycaemia induced movement disorders, such as hemiballism are rare disorders. The syndrome is characterised by the triad of hemiballism, contralateral T1-hyperintense striatal lesion and non-ketotic hyperglycaemia. Here we report a patient with untreated diabetes presenting with acute onset of hemiballism. MRI revealed T1 hyperintensity of the head of the caudate nucleus and the anterior putamen. The patient also had acantocytosis. Based on the detailed examination of the neuroradiological results and earlier findings we will discuss the pathomechanism. Based on previous findings microhemorrhages, extensive mineralisation, gemistocytic astrocytosis might play a role in the development of the imaging signs. The connectivity pattern of the striatal lesion showed extensive connections to the frontal cortex. In coexistence with that the most severe impairment was found on the phonemic verbal fluency task measuring frontal executive functions.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Speech Disorders
/
Cognition Disorders
/
Corpus Striatum
/
Dyskinesias
/
Executive Function
/
Frontal Lobe
/
Hyperglycemia
Type of study:
Etiology_studies
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Ideggyogy Sz
Year:
2015
Document type:
Article