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Low Beclin-1 expression predicts improved overall survival in patients treated with immunomodulatory drugs for multiple myeloma and identifies autophagy inhibition as a promising potentially druggable new therapeutic target: an analysis from The Austrian Myeloma Registry (AMR).
Willenbacher, Wolfgang; Thangavadivel, Shanmugapriya; Greil, Richard; Willenbacher, Ella; Weger, Roman; Manzl, Claudia; Jöhrer, Karin; Brunner, Andrea.
Affiliation
  • Willenbacher W; a Department of Internal Medicine , University Hospital for Internal Medicine V (Haematology and Oncology), Medical University of Innsbruck , Innsbruck , Austria ;
  • Thangavadivel S; b Area 4 Health Technology Assessment and Bioinformatics , ONCOTYROL - Center for Personalized Cancer Medicine , Innsbruck , Austria ;
  • Greil R; c Tyrolean Cancer Research Institute , Innsbruck , Austria ;
  • Willenbacher E; c Tyrolean Cancer Research Institute , Innsbruck , Austria ;
  • Weger R; d Laboratory of Immunological and Molecular Cancer Research , Salzburg Cancer Research Institute , Salzburg , Austria ;
  • Manzl C; a Department of Internal Medicine , University Hospital for Internal Medicine V (Haematology and Oncology), Medical University of Innsbruck , Innsbruck , Austria ;
  • Jöhrer K; b Area 4 Health Technology Assessment and Bioinformatics , ONCOTYROL - Center for Personalized Cancer Medicine , Innsbruck , Austria ;
  • Brunner A; e Department of Pathology, Division of General Pathology , Medical University of Innsbruck , Innsbruck , Austria.
Leuk Lymphoma ; 57(10): 2330-41, 2016 10.
Article in En | MEDLINE | ID: mdl-26880040
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression / Beclin-1 / Immunologic Factors / Multiple Myeloma / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2016 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression / Beclin-1 / Immunologic Factors / Multiple Myeloma / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2016 Document type: Article Country of publication: Estados Unidos