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The viral G protein-coupled receptor ORF74 unmasks phospholipase C signaling of the receptor tyrosine kinase IGF-1R.
de Munnik, Sabrina M; van der Lee, Rosan; Velders, Daniëlle M; van Offenbeek, Jody; Smits-de Vries, Laura; Leurs, Rob; Smit, Martine J; Vischer, Henry F.
Affiliation
  • de Munnik SM; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • van der Lee R; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • Velders DM; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • van Offenbeek J; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • Smits-de Vries L; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • Leurs R; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • Smit MJ; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands.
  • Vischer HF; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands. Electronic address: h.f.vischer@vu.nl.
Cell Signal ; 28(6): 595-605, 2016 Jun.
Article in En | MEDLINE | ID: mdl-26931381
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Type C Phospholipases / Viral Proteins / Signal Transduction / Receptor, IGF Type 1 / Receptors, Chemokine Limits: Humans Language: En Journal: Cell Signal Year: 2016 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Type C Phospholipases / Viral Proteins / Signal Transduction / Receptor, IGF Type 1 / Receptors, Chemokine Limits: Humans Language: En Journal: Cell Signal Year: 2016 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido