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PGE2 receptor EP3 inhibits water reabsorption and contributes to polyuria and kidney injury in a streptozotocin-induced mouse model of diabetes.
Hassouneh, Ramzi; Nasrallah, Rania; Zimpelmann, Joe; Gutsol, Alex; Eckert, David; Ghossein, Jamie; Burns, Kevin D; Hébert, Richard L.
Affiliation
  • Hassouneh R; Department of Cellular and Molecular Medicine, Kidney Research Centre, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada, K1H 8M5.
  • Nasrallah R; Department of Cellular and Molecular Medicine, Kidney Research Centre, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada, K1H 8M5.
  • Zimpelmann J; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
  • Gutsol A; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
  • Eckert D; Department of Cellular and Molecular Medicine, Kidney Research Centre, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada, K1H 8M5.
  • Ghossein J; Department of Cellular and Molecular Medicine, Kidney Research Centre, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada, K1H 8M5.
  • Burns KD; Department of Cellular and Molecular Medicine, Kidney Research Centre, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada, K1H 8M5.
  • Hébert RL; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
Diabetologia ; 59(6): 1318-28, 2016 06.
Article in En | MEDLINE | ID: mdl-26995650
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyuria / Water / Streptozocin / Receptors, Prostaglandin E / Receptors, Prostaglandin E, EP3 Subtype / Kidney Type of study: Prognostic_studies Limits: Animals Language: En Journal: Diabetologia Year: 2016 Document type: Article Country of publication: Alemania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyuria / Water / Streptozocin / Receptors, Prostaglandin E / Receptors, Prostaglandin E, EP3 Subtype / Kidney Type of study: Prognostic_studies Limits: Animals Language: En Journal: Diabetologia Year: 2016 Document type: Article Country of publication: Alemania