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AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.
Weir, Hazel M; Bradbury, Robert H; Lawson, Mandy; Rabow, Alfred A; Buttar, David; Callis, Rowena J; Curwen, Jon O; de Almeida, Camila; Ballard, Peter; Hulse, Michael; Donald, Craig S; Feron, Lyman J L; Karoutchi, Galith; MacFaul, Philip; Moss, Thomas; Norman, Richard A; Pearson, Stuart E; Tonge, Michael; Davies, Gareth; Walker, Graeme E; Wilson, Zena; Rowlinson, Rachel; Powell, Steve; Sadler, Claire; Richmond, Graham; Ladd, Brendon; Pazolli, Ermira; Mazzola, Anne Marie; D'Cruz, Celina; De Savi, Chris.
Affiliation
  • Weir HM; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom. Hazel.Weir@astrazeneca.com.
  • Bradbury RH; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Lawson M; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Rabow AA; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Buttar D; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Callis RJ; Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Curwen JO; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • de Almeida C; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Ballard P; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Hulse M; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Donald CS; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Feron LJ; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Karoutchi G; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • MacFaul P; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Moss T; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Norman RA; Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Pearson SE; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Tonge M; Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Davies G; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Walker GE; Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Wilson Z; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Rowlinson R; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Powell S; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Sadler C; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Richmond G; Oncology iMed, AstraZeneca, Alderley Park, Macclesfield, United Kingdom.
  • Ladd B; Oncology iMed, AstraZeneca R&D Boston, Gatehouse Drive, Waltham, Massachusetts.
  • Pazolli E; H3 Biomedicine, Cambridge, Massachusetts.
  • Mazzola AM; Oncology iMed, AstraZeneca R&D Boston, Gatehouse Drive, Waltham, Massachusetts.
  • D'Cruz C; Oncology iMed, AstraZeneca R&D Boston, Gatehouse Drive, Waltham, Massachusetts.
  • De Savi C; Oncology iMed, AstraZeneca R&D Boston, Gatehouse Drive, Waltham, Massachusetts.
Cancer Res ; 76(11): 3307-18, 2016 06 01.
Article in En | MEDLINE | ID: mdl-27020862
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Cinnamates / Estrogen Receptor Modulators / Estrogen Receptor alpha / Indoles / Mutation Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2016 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Cinnamates / Estrogen Receptor Modulators / Estrogen Receptor alpha / Indoles / Mutation Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2016 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos