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NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.
de Valle, Elisha; Grigoriadis, George; O'Reilly, Lorraine A; Willis, Simon N; Maxwell, Mhairi J; Corcoran, Lynn M; Tsantikos, Evelyn; Cornish, Jasper K S; Fairfax, Kirsten A; Vasanthakumar, Ajithkumar; Febbraio, Mark A; Hibbs, Margaret L; Pellegrini, Marc; Banerjee, Ashish; Hodgkin, Philip D; Kallies, Axel; Mackay, Fabienne; Strasser, Andreas; Gerondakis, Steve; Gugasyan, Raffi.
Affiliation
  • de Valle E; Burnet Institute, Melbourne, VIC 3004, Australia Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Grigoriadis G; School of Clinical Sciences, Monash University, Melbourne, VIC 3004, Australia Center for Cancer Research, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia Clinical Haematology, Monash and Alfred Health, Melbourne, VIC 3168, Australia.
  • O'Reilly LA; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Willis SN; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Maxwell MJ; Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Corcoran LM; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Tsantikos E; Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Cornish JK; Burnet Institute, Melbourne, VIC 3004, Australia Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Fairfax KA; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Vasanthakumar A; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Febbraio MA; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.
  • Hibbs ML; Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Pellegrini M; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Banerjee A; Center for Cancer Research, Hudson Institute of Medical Research, Melbourne, VIC 3168, Australia.
  • Hodgkin PD; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Kallies A; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Mackay F; Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Strasser A; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia Department of Medical Biology, University of Melbourne, Melbourne, VIC 3050, Australia.
  • Gerondakis S; Infection and Immunity Program, Monash Biomedical Discovery Institute, Monash University, Melbourne, VIC 3004, Australia Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3004, Australia.
  • Gugasyan R; Burnet Institute, Melbourne, VIC 3004, Australia Immunology, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia gugasyan@burnet.edu.au.
J Exp Med ; 213(4): 621-41, 2016 Apr 04.
Article in En | MEDLINE | ID: mdl-27022143
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Transcription, Genetic / B-Lymphocytes / Interleukin-6 / Germinal Center / NF-kappa B p50 Subunit Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Exp Med Year: 2016 Document type: Article Affiliation country: Australia
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Transcription, Genetic / B-Lymphocytes / Interleukin-6 / Germinal Center / NF-kappa B p50 Subunit Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Exp Med Year: 2016 Document type: Article Affiliation country: Australia