Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis.

Meyer, Kathleen; Hodwin, Bettina; Ramanujam, Deepak; Engelhardt, Stefan; Sarikas, Antonio

Meyer, Kathleen; Hodwin, Bettina; Ramanujam, Deepak; Engelhardt, Stefan; Sarikas, Antonio.

Affiliation

Meyer K; Institute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), partner site Munich Heart Alliance, Munich, Germany.
Hodwin B; Institute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany.
Ramanujam D; Institute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), partner site Munich Heart Alliance, Munich, Germany.
Engelhardt S; Institute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), partner site Munich Heart Alliance, Munich, Germany.
Sarikas A; Institute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), partner site Munich Heart Alliance, Munich, Germany. Electronic address: antonio.sarikas@tum.de.

J Am Coll Cardiol ; 67(17): 2018-28, 2016 05 03.

Article in En | MEDLINE | ID: mdl-27126529

Subject(s)
Key words

antifibrotic therapy; cardiac fibroblasts; extracellular matrix; gene therapy; transverse aortic constriction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellular Senescence / Myofibroblasts / Myocardium Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Am Coll Cardiol Year: 2016 Document type: Article Affiliation country: Alemania

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