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MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis.
Yan, Shiju; Wang, Meng; Zhao, Jian; Zhang, Hongtao; Zhou, Chengpei; Jin, Lei; Zhang, Yinglong; Qiu, Xiuchun; Ma, Baoan; Fan, Qingyu.
Affiliation
  • Yan S; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Wang M; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Zhao J; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Zhang H; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Zhou C; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Jin L; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Zhang Y; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Qiu X; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Ma B; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
  • Fan Q; Department of Orthopedics, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Int J Mol Med ; 38(1): 201-9, 2016 Jul.
Article in En | MEDLINE | ID: mdl-27247228
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Signal Transduction / Tumor Suppressor Protein p53 / Apoptosis / Chondrocytes / MicroRNAs / Sirtuin 1 Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male / Middle aged Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2016 Document type: Article Country of publication: Grecia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Signal Transduction / Tumor Suppressor Protein p53 / Apoptosis / Chondrocytes / MicroRNAs / Sirtuin 1 Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male / Middle aged Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2016 Document type: Article Country of publication: Grecia