Dexmedetomidine increases acetylation level of histone through ERK1/2 pathway in dopamine neuron.

Hu, S-P; Zhao, J-J; Wang, W-X; Liu, Y; Wu, H-F; Chen, C; Yu, L; Gui, J-B

Hu, S-P; Zhao, J-J; Wang, W-X; Liu, Y; Wu, H-F; Chen, C; Yu, L; Gui, J-B.

Affiliation

Hu SP; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Zhao JJ; 2 Department of Orthopedics, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Wang WX; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Liu Y; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Wu HF; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Chen C; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Yu L; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.
Gui JB; 1 Department of Anesthesiology, Huzhou Central Hospital, Huzhou, Zhejiang, People's Republic of China.

Hum Exp Toxicol ; 36(5): 474-482, 2017 May.

Article in En | MEDLINE | ID: mdl-27334975

Subject(s)
Key words

Dexmedetomidine; Htr signal; histone acetylation; neuroprotection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Neuroprotective Agents / Dexmedetomidine / Extracellular Signal-Regulated MAP Kinases / Dopaminergic Neurons Limits: Animals Language: En Journal: Hum Exp Toxicol Journal subject: TOXICOLOGIA Year: 2017 Document type: Article Country of publication: Reino Unido

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