Three-day regimen of oseltamivir for postexposure prophylaxis of influenza in wards.
J Hosp Infect
; 94(2): 150-3, 2016 Oct.
Article
in En
| MEDLINE
| ID: mdl-27346624
ABSTRACT
Inpatients who had been in close contact with patients with influenza were given oseltamivir [75mg capsules once daily for adults or 2mg/kg (maximum of 75mg) once daily for children] for three days as postexposure prophylaxis (PEP). The index patients with influenza were prescribed a neuraminidase inhibitor and were discharged immediately or transferred to isolation rooms. The protective efficacy of oseltamivir for three days was 93% overall [95% confidence interval (CI) 53-99%; P=0.023] and 94% for influenza A (95% CI 61-99%; P=0.017), which is comparable to that of seven- to 10-day regimens of oseltamivir as PEP.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Chemoprevention
/
Influenza, Human
/
Oseltamivir
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Post-Exposure Prophylaxis
Limits:
Adult
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Aged
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Female
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
J Hosp Infect
Year:
2016
Document type:
Article