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Sphingosine 1­phosphate induced by hypoxia increases the expression of PAI­1 in HepG2 cells via HIF­1α.
Sanagawa, Akimasa; Iwaki, Soichiro; Asai, Moyoko; Sakakibara, Daisuke; Norimoto, Hiroaki; Sobel, Burton E; Fujii, Satoshi.
Affiliation
  • Sanagawa A; Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 467­8603, Japan.
  • Iwaki S; Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 467­8603, Japan.
  • Asai M; Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 467­8603, Japan.
  • Sakakibara D; Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 467­8603, Japan.
  • Norimoto H; Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 467­8603, Japan.
  • Sobel BE; Cardiovascular Research Institute, University of Vermont, Colchester, VT 05446, USA.
  • Fujii S; Department of Molecular and Cellular Pathobiology and Therapeutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 467­8603, Japan.
Mol Med Rep ; 14(2): 1841-8, 2016 Aug.
Article in En | MEDLINE | ID: mdl-27357063
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sphingosine / Lysophospholipids / Gene Expression Regulation, Neoplastic / Plasminogen Activator Inhibitor 1 / Hypoxia-Inducible Factor 1, alpha Subunit / Hypoxia Limits: Humans Language: En Journal: Mol Med Rep Year: 2016 Document type: Article Affiliation country: Japón Country of publication: Grecia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sphingosine / Lysophospholipids / Gene Expression Regulation, Neoplastic / Plasminogen Activator Inhibitor 1 / Hypoxia-Inducible Factor 1, alpha Subunit / Hypoxia Limits: Humans Language: En Journal: Mol Med Rep Year: 2016 Document type: Article Affiliation country: Japón Country of publication: Grecia