[Effectiveness of heparin versus 0.9% saline solution in maintaining the permeability of central venous catheters: a systematic review]. / Eficácia da heparina e soro fisiológico para manter a permeabilidade dos cateteres venosos centrais: revisão sistemática.
Rev Esc Enferm USP
; 49(6): 999-1007, 2015 Dec.
Article
in Pt
| MEDLINE
| ID: mdl-27419685
ABSTRACT
OBJECTIVE:
Determining which is the most effective solution (heparin flush compared to 0.9% saline flush) for reducing the risk of occlusions in central venous catheters (CVC) in adults.METHOD:
The systematic review followed the principles proposed by the Cochrane Handbook; critical analysis, extraction and synthesis of data were performed by two independent researchers; statistical analysis was performed using the RevMan program 5.2.8.RESULTS:
Eight randomized controlled trials and one cohort study were included and the results of the meta-analysis showed no difference (RR=0.68, 95% CI=0.41-1.10; p=0.12). Analysis by subgroups showed that there was no difference in fully deployed CVC (RR=1.09, CI 95%=0.53-2.22; p=0.82); Multi-Lumen CVC showed beneficial effects in the heparin group (RR=0.53, CI 95%=0.29-0.95; p=0.03); in Double-Lumen CVC for hemodialysis (RR=1.18, CI 95%=0.08-17.82; p=0.90) and Peripherally inserted CVC (RR=0.14, CI 95%=0.01-2.60; p=0.19) also showed no difference.CONCLUSION:
Saline solution is sufficient for maintaining patency of the central venous catheter, preventing the risks associated with heparin administration.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Heparin
/
Sodium Chloride
/
Central Venous Catheters
/
Anticoagulants
Type of study:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
/
Systematic_reviews
Limits:
Humans
Language:
Pt
Journal:
Rev Esc Enferm USP
Year:
2015
Document type:
Article
Affiliation country:
Portugal