[Pathogenic factors in calcium oxalate stones: Epidemiological investigation]. / Recherche de facteurs lithogènes au cours des lithiases oxalo-calciques : enquête épidémiologique.
Prog Urol
; 26(8): 450-6, 2016 Jun.
Article
in Fr
| MEDLINE
| ID: mdl-27430498
ABSTRACT
INTRODUCTION:
Calcium oxalate stones are the most common urolithiasis. Changes in dietary habits, socio-economic and health status of populations explain its progression. The aim of our study was to determine metabolic factors leading to lithiasis and clarify its causes. PATIENTS ANDMETHODS:
This is a retrospective study of 100 patients with calcium oxalate stones identified by morpho-constitutional study, collected in our department over a period of 5 years (2008-2013). We analyzed clinical, radiological and metabolic data.RESULTS:
They were 73 men and 27 women (gender ratio 2.7), aged meanly of 44.8 years. Dietary survey revealed inadequate calcium intake in 87% of cases. Urinary abnormalities were hypocitraturia (34%), hypomagnesuria (32%) and outflow hypercalciuria (21%). Crystalluria was positive in 44% of cases. Whewellite was the most common crystalline form. Calculi were bilateral (53%), renal (85%) and mainly collected after urological procedures (74%). Infrared analysis showed that 81% of stones have a heterogeneous composition. Pure Whewellite or combined with other compounds was the most frequent (31%). Idiopathic calcium oxalate lithiasis was the most common etiology (69%). Among secondary etiologies, diabetes was most frequently found (10%).CONCLUSION:
Our epidemiological study of calcium oxalate stones has allowed us to identify the high frequency of food hyperoxaluria partly explained by a low calcium intake and a diet rich in oxalate phytotherapy. LEVEL OF EVIDENCE 4.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Calcium Oxalate
/
Urolithiasis
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Fr
Journal:
Prog Urol
Journal subject:
UROLOGIA
Year:
2016
Document type:
Article
Affiliation country:
Túnez