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The TGFß-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration.
Tjomsland, Vegard; Sandnes, Dagny; Pomianowska, Ewa; Cizmovic, Smiljana Torbica; Aasrum, Monica; Brusevold, Ingvild Johnsen; Christoffersen, Thoralf; Gladhaug, Ivar P.
Affiliation
  • Tjomsland V; Department of Hepato-pancreato-biliary Surgery, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. vegard.tjomsland@medisin.uio.no.
  • Sandnes D; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. vegard.tjomsland@medisin.uio.no.
  • Pomianowska E; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Cizmovic ST; Department of Hepato-pancreato-biliary Surgery, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Aasrum M; Department of Hepato-pancreato-biliary Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
  • Brusevold IJ; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Christoffersen T; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Gladhaug IP; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
J Exp Clin Cancer Res ; 35(1): 122, 2016 07 29.
Article in En | MEDLINE | ID: mdl-27473228
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Transforming Growth Factor beta / Smad3 Protein / Interleukin-1alpha / Pancreatic Stellate Cells Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Exp Clin Cancer Res Year: 2016 Document type: Article Affiliation country: Noruega Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Transforming Growth Factor beta / Smad3 Protein / Interleukin-1alpha / Pancreatic Stellate Cells Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Exp Clin Cancer Res Year: 2016 Document type: Article Affiliation country: Noruega Country of publication: Reino Unido