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Macrophages induce resistance to 5-fluorouracil chemotherapy in colorectal cancer through the release of putrescine.
Zhang, Xuan; Chen, Yujuan; Hao, Lijun; Hou, Along; Chen, Xiaozhen; Li, Yifei; Wang, Rui; Luo, Peng; Ruan, Zhihua; Ou, Juanjuan; Shi, Chunmeng; Miao, Hongming; Liang, Houjie.
Affiliation
  • Zhang X; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Chen Y; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Hao L; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Hou A; Department of Biochemistry and Molecular Biology, Third Military Medical University, Chongqing 400038, China.
  • Chen X; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Li Y; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Wang R; Department of Biochemistry and Molecular Biology, Third Military Medical University, Chongqing 400038, China.
  • Luo P; Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
  • Ruan Z; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Ou J; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  • Shi C; Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
  • Miao H; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China; Department of Biochemistry and Molecular Biology, Third Military Medical University, Chongqing 400038, China. Electronic address: hongmingmiao@sina.com.
  • Liang H; Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Electronic address: lianghoujie@sina.com.
Cancer Lett ; 381(2): 305-13, 2016 10 28.
Article in En | MEDLINE | ID: mdl-27514455

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Putrescine / Apoptosis / Macrophages, Peritoneal / Drug Resistance, Neoplasm / Fluorouracil / Antimetabolites, Antineoplastic Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Lett Year: 2016 Document type: Article Affiliation country: China Country of publication: Irlanda

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Putrescine / Apoptosis / Macrophages, Peritoneal / Drug Resistance, Neoplasm / Fluorouracil / Antimetabolites, Antineoplastic Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Lett Year: 2016 Document type: Article Affiliation country: China Country of publication: Irlanda