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Design, rationale, and baseline characteristics of the randomized double-blind phase II clinical trial of ibudilast in progressive multiple sclerosis.
Fox, Robert J; Coffey, Christopher S; Cudkowicz, Merit E; Gleason, Trevis; Goodman, Andrew; Klawiter, Eric C; Matsuda, Kazuko; McGovern, Michelle; Conwit, Robin; Naismith, Robert; Ashokkumar, Akshata; Bermel, Robert; Ecklund, Dixie; Koepp, Maxine; Long, Jeffrey; Natarajan, Sneha; Ramachandran, Srividya; Skaramagas, Thomai; Thornell, Brenda; Yankey, Jon; Agius, Mark; Bashir, Khurram; Cohen, Bruce; Coyle, Patricia; Delgado, Silvia; Dewitt, Dana; Flores, Angela; Giesser, Barbara; Goldman, Myla; Jubelt, Burk; Lava, Neil; Lynch, Sharon; Miravalle, Augusto; Moses, Harold; Ontaneda, Daniel; Perumal, Jai; Racke, Michael; Repovic, Pavle; Riley, Claire; Severson, Christopher; Shinnar, Shlomo; Suski, Valerie; Weinstock-Gutman, Bianca; Yadav, Vijayshree; Zabeti, Aram.
Affiliation
  • Fox RJ; Cleveland Clinic, Neurological Institute, Cleveland, OH, United States. Electronic address: foxr@ccf.org.
  • Coffey CS; Data Coordinating Center, NeuroNEXT, University of Iowa, Iowa City, IA, United States.
  • Cudkowicz ME; Clinical Coordinating Center, NeuroNEXT, Harvard Partners, Boston, MA, United States.
  • Gleason T; Patient Advocate, Seattle, WA, United States.
  • Goodman A; University of Rochester Medical Center, Rochester, NY, United States.
  • Klawiter EC; Massachusetts General Hospital, Boston, MA, United States.
  • Matsuda K; Medicinova Inc., La Jolla, CA, United States.
  • McGovern M; Clinical Coordinating Center, NeuroNEXT, Harvard Partners, Boston, MA, United States.
  • Conwit R; National Institutes of Neurological Disease and Stroke, Bethesda, MD, United States.
  • Naismith R; Washington University School of Medicine, St. Louis, MO, United States.
  • Ashokkumar A; Data Coordinating Center, NeuroNEXT, University of Iowa, Iowa City, IA, United States.
  • Bermel R; Cleveland Clinic, Neurological Institute, Cleveland, OH, United States.
  • Ecklund D; Data Coordinating Center, NeuroNEXT, University of Iowa, Iowa City, IA, United States.
  • Koepp M; Data Coordinating Center, NeuroNEXT, University of Iowa, Iowa City, IA, United States.
  • Long J; Data Coordinating Center, NeuroNEXT, University of Iowa, Iowa City, IA, United States.
  • Natarajan S; Cleveland Clinic, Neurological Institute, Cleveland, OH, United States.
  • Ramachandran S; Cleveland Clinic, Neurological Institute, Cleveland, OH, United States.
  • Skaramagas T; Cleveland Clinic, Neurological Institute, Cleveland, OH, United States.
  • Thornell B; Clinical Coordinating Center, NeuroNEXT, Harvard Partners, Boston, MA, United States.
  • Yankey J; Data Coordinating Center, NeuroNEXT, University of Iowa, Iowa City, IA, United States.
  • Agius M; University of California at Davis, Sacramento, CA; currently at Barrows Neurological Institute, Phoenix, AZ, United States.
  • Bashir K; University of Alabama at Birmingham, Birmingham, AL, United States.
  • Cohen B; Northwestern University, Chicago, IL, United States.
  • Coyle P; State University of New York, Stony Brook, NY, United States.
  • Delgado S; University of Miami School of Medicine, Miami, FL, United States.
  • Dewitt D; University of Utah, Salt Lake City, UT, United States.
  • Flores A; University of Texas Southwestern Medical Center, Dallas, TX, United States.
  • Giesser B; University of California at Los Angeles, Los Angeles, CA, United States.
  • Goldman M; University of Virginia at Charlottesville, Charlottesville, VA, United States.
  • Jubelt B; State University of New York Upstate Medical University, Syracuse, NY, United States.
  • Lava N; Emory University, Atlanta, GA, United States.
  • Lynch S; University of Kansas Medical Center, Kansas City, KS, United States.
  • Miravalle A; University of Colorado at Denver, Aurora, CO, United States.
  • Moses H; Vanderbilt University, Nashville, TN, United States.
  • Ontaneda D; Cleveland Clinic, Neurological Institute, Cleveland, OH, United States.
  • Perumal J; Weill Cornell Medical College, New York, NY, United States.
  • Racke M; The Ohio State University, Columbus, OH, United States.
  • Repovic P; Swedish Medical Center at Seattle, Seattle, WA, United States.
  • Riley C; Columbia University Medical Center, New York, NY, United States.
  • Severson C; Brigham and Women's Hospital, Brookline, MA, United States.
  • Shinnar S; Montefiore Medical Center, Bronx, NY, United States.
  • Suski V; University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
  • Weinstock-Gutman B; State University of New York Buffalo, Buffalo, NY, United States.
  • Yadav V; Oregon Health and Science University, Portland, OR, United States.
  • Zabeti A; University of Cincinnati, Cincinnati, OH, United States.
Contemp Clin Trials ; 50: 166-77, 2016 09.
Article in En | MEDLINE | ID: mdl-27521810
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Pyridines / Multiple Sclerosis, Chronic Progressive Type of study: Clinical_trials Aspects: Patient_preference Limits: Adult / Humans / Middle aged Language: En Journal: Contemp Clin Trials Journal subject: MEDICINA / TERAPEUTICA Year: 2016 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Pyridines / Multiple Sclerosis, Chronic Progressive Type of study: Clinical_trials Aspects: Patient_preference Limits: Adult / Humans / Middle aged Language: En Journal: Contemp Clin Trials Journal subject: MEDICINA / TERAPEUTICA Year: 2016 Document type: Article Country of publication: Estados Unidos