Imaging features of undifferentiated embryonal sarcoma of the liver: a series of 15 children.
Pediatr Radiol
; 46(12): 1694-1704, 2016 Nov.
Article
in En
| MEDLINE
| ID: mdl-27562247
ABSTRACT
BACKGROUND:
Undifferentiated embryonal sarcoma of the liver is a rare malignant mesenchymal tumour occurring mostly in children ages 6-10 years. The discrepancy between its solid appearance on US and cystic-like appearance on CT has been described.OBJECTIVE:
To study the imaging particularities and similarities among our cases of undifferentiated embryonal sarcoma and to report the errors in initial diagnoses. MATERIALS ANDMETHODS:
We conducted a retrospective study of 15 children with undifferentiated embryonal sarcoma diagnosed or referred to our hospital during 1997-2015 and analysed the clinical, biological and imaging data.RESULTS:
We identified eight boys and seven girls ages 9 months to 14 years. Ten children presented with abdominal pain. Alpha-fetoprotein was slightly increased in one. Initial US and CT had been performed for all, while additional MRI had been done in two children. Initial CT demonstrated a hypoattenuated mass in all. Rupture was seen in five and intratumoural bleeding in seven children. Tumour volumes reduced during neoadjuvant chemotherapy in 10 children.CONCLUSION:
Undifferentiated embryonal sarcoma might be suggested in a non-secreting unifocal tumour with well-defined borders, fluid-filled spaces on US, hypoattenuation and serpiginous vessels on CT, and if there are signs of internal bleeding or rupture on CT or MRI.Key words
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoma
/
Magnetic Resonance Imaging
/
Tomography, X-Ray Computed
/
Ultrasonography
/
Neoplasms, Germ Cell and Embryonal
/
Liver Neoplasms
Type of study:
Diagnostic_studies
/
Observational_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Pediatr Radiol
Year:
2016
Document type:
Article
Affiliation country:
Francia