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Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude.
Kantae, Vasudev; Krekels, Elke H J; Ordas, Anita; González, Oskar; van Wijk, Rob C; Harms, Amy C; Racz, Peter I; van der Graaf, Piet H; Spaink, Herman P; Hankemeier, Thomas.
Affiliation
  • Kantae V; 1 Division of Analytical Biosciences, Systems Pharmacology Cluster, Leiden Academic Centre for Drug Research, Leiden University , Leiden, The Netherlands .
  • Krekels EH; 2 Division of Pharmacology, Systems Pharmacology Cluster, Leiden Academic Centre for Drug Research, Leiden University , Leiden, The Netherlands .
  • Ordas A; 3 IBL, Institute of Biology, Leiden University , Leiden, the Netherlands .
  • González O; 1 Division of Analytical Biosciences, Systems Pharmacology Cluster, Leiden Academic Centre for Drug Research, Leiden University , Leiden, The Netherlands .
  • van Wijk RC; 4 Science and Technology Faculty, Analytical Chemistry Department, University of the Basque Country/EHU , Bilbao, Spain .
  • Harms AC; 2 Division of Pharmacology, Systems Pharmacology Cluster, Leiden Academic Centre for Drug Research, Leiden University , Leiden, The Netherlands .
  • Racz PI; 1 Division of Analytical Biosciences, Systems Pharmacology Cluster, Leiden Academic Centre for Drug Research, Leiden University , Leiden, The Netherlands .
  • van der Graaf PH; 5 ZF-screens B.V. , Leiden, The Netherlands .
  • Spaink HP; 2 Division of Pharmacology, Systems Pharmacology Cluster, Leiden Academic Centre for Drug Research, Leiden University , Leiden, The Netherlands .
  • Hankemeier T; 3 IBL, Institute of Biology, Leiden University , Leiden, the Netherlands .
Zebrafish ; 13(6): 504-510, 2016 12.
Article in En | MEDLINE | ID: mdl-27632065
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zebrafish / Analgesics, Non-Narcotic / Drug Evaluation, Preclinical / Acetaminophen / Models, Theoretical Type of study: Prognostic_studies Limits: Animals Language: En Journal: Zebrafish Journal subject: BIOLOGIA Year: 2016 Document type: Article Affiliation country: Países Bajos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zebrafish / Analgesics, Non-Narcotic / Drug Evaluation, Preclinical / Acetaminophen / Models, Theoretical Type of study: Prognostic_studies Limits: Animals Language: En Journal: Zebrafish Journal subject: BIOLOGIA Year: 2016 Document type: Article Affiliation country: Países Bajos Country of publication: Estados Unidos