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Identification of fused bicyclic derivatives of pyrrolidine and imidazolidinone as dengue virus-2 NS2B-NS3 protease inhibitors.
Weng, Zhibing; Shao, Xiaoxia; Graf, Dominik; Wang, Chunguang; Klein, Christian D; Wang, Jing; Zhou, Guo-Chun.
Affiliation
  • Weng Z; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, Jiangsu, PR China.
  • Shao X; Institute of Protein Research, Tongji University, Shanghai 200092, PR China.
  • Graf D; Medicinal Chemistry, Institute of Pharmacy and Molecular Biotechnology IPMB, Heidelberg University, Im Neuenheimer Feld 364 D-69120, Heidelberg, Germany.
  • Wang C; Institute of Protein Research, Tongji University, Shanghai 200092, PR China.
  • Klein CD; Medicinal Chemistry, Institute of Pharmacy and Molecular Biotechnology IPMB, Heidelberg University, Im Neuenheimer Feld 364 D-69120, Heidelberg, Germany.
  • Wang J; College of Sciences, Nanjing Agricultural University, Nanjing 210095, Jiangsu, PR China. Electronic address: wangjing@njau.edu.cn.
  • Zhou GC; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, Jiangsu, PR China. Electronic address: gczhou@njtech.edu.cn.
Eur J Med Chem ; 125: 751-759, 2017 Jan 05.
Article in En | MEDLINE | ID: mdl-27721158
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Dengue Virus / Imidazolidines Type of study: Diagnostic_studies Language: En Journal: Eur J Med Chem Year: 2017 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Dengue Virus / Imidazolidines Type of study: Diagnostic_studies Language: En Journal: Eur J Med Chem Year: 2017 Document type: Article