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Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer.
Li, Hongde; Stokes, William; Chater, Emily; Roy, Rajat; de Bruin, Elza; Hu, Yili; Liu, Zhigang; Smit, Egbert F; Heynen, Guus Jje; Downward, Julian; Seckl, Michael J; Wang, Yulan; Tang, Huiru; Pardo, Olivier E.
Affiliation
  • Li H; State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Centre for Genetics and Development, Shanghai International Centre for Molecular Phenomics, Metabonomics and Systems Biology Laboratory, Department of Biochemistry
  • Stokes W; Division of Cancer, Department of Surgery and Cancer, Imperial College, Hammersmith Hospital , London, UK.
  • Chater E; Division of Cancer, Department of Surgery and Cancer, Imperial College, Hammersmith Hospital , London, UK.
  • Roy R; Division of Cancer, Department of Surgery and Cancer, Imperial College, Hammersmith Hospital , London, UK.
  • de Bruin E; Signal Transduction Laboratory, CRUK London Research Institute, London, UK; Personalised Healthcare & Biomarkers, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, UK.
  • Hu Y; Key Laboratory of Magnetic Resonance in Biological Systems, National Centre for Magnetic Resonance in Wuhan, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences , Wuhan, China.
  • Liu Z; Key Laboratory of Magnetic Resonance in Biological Systems, National Centre for Magnetic Resonance in Wuhan, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences , Wuhan, China.
  • Smit EF; Department of Pulmonary Diseases, VU University Medical Centre, Netherlands Cancer Institute , Amsterdam, Netherlands.
  • Heynen GJ; Section of Molecular Carcinogenesis, Netherlands Cancer Institute , Amsterdam, Netherlands.
  • Downward J; Signal Transduction Laboratory, CRUK London Research Institute , London, UK.
  • Seckl MJ; Division of Cancer, Department of Surgery and Cancer, Imperial College, Hammersmith Hospital , London, UK.
  • Wang Y; Key Laboratory of Magnetic Resonance in Biological Systems, National Centre for Magnetic Resonance in Wuhan, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, China; Collaborative Innovation Ce
  • Tang H; State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Centre for Genetics and Development, Shanghai International Centre for Molecular Phenomics, Metabonomics and Systems Biology Laboratory, Department of Biochemistry
  • Pardo OE; Division of Cancer, Department of Surgery and Cancer, Imperial College, Hammersmith Hospital , London, UK.
Cell Discov ; 2: 16031, 2016.
Article in En | MEDLINE | ID: mdl-27721983
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Cell Discov Year: 2016 Document type: Article Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Cell Discov Year: 2016 Document type: Article Country of publication: Reino Unido