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Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer.
Murphy, Adrian G; Casey, Rory; Maguire, Aoife; Tosetto, Miriam; Butler, Clare T; Conroy, Emer; Reynolds, Alison L; Sheahan, Kieran; O'Donoghue, Diarmuid; Gallagher, William M; Fennelly, David; Kennedy, Breandán N; O'Sullivan, Jacintha.
Affiliation
  • Murphy AG; Centre for Colorectal Disease, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
  • Casey R; UCD School of Biomolecular and Biomedical Science Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Maguire A; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.
  • Tosetto M; Department of Histopathology, St. James's Hospital, Dublin 8, Ireland.
  • Butler CT; Centre for Colorectal Disease, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
  • Conroy E; UCD School of Biomolecular and Biomedical Science Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Reynolds AL; UCD School of Biomolecular and Biomedical Science Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Sheahan K; UCD School of Biomolecular and Biomedical Science Conway Institute, University College Dublin, Dublin 4, Ireland.
  • O'Donoghue D; Centre for Colorectal Disease, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
  • Gallagher WM; Centre for Colorectal Disease, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
  • Fennelly D; UCD School of Biomolecular and Biomedical Science Conway Institute, University College Dublin, Dublin 4, Ireland.
  • Kennedy BN; Centre for Colorectal Disease, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
  • O'Sullivan J; UCD School of Biomolecular and Biomedical Science Conway Institute, University College Dublin, Dublin 4, Ireland.
Sci Rep ; 6: 34523, 2016 10 14.
Article in En | MEDLINE | ID: mdl-27739445

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Quinolines / Colorectal Neoplasms / Angiogenesis Inhibitors / Neovascularization, Pathologic / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Irlanda Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Quinolines / Colorectal Neoplasms / Angiogenesis Inhibitors / Neovascularization, Pathologic / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Irlanda Country of publication: Reino Unido