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Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.
Faião-Flores, F; Alves-Fernandes, D K; Pennacchi, P C; Sandri, S; Vicente, A L S A; Scapulatempo-Neto, C; Vazquez, V L; Reis, R M; Chauhan, J; Goding, C R; Smalley, K S; Maria-Engler, S S.
Affiliation
  • Faião-Flores F; Department of Clinical Chemistry and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Alves-Fernandes DK; Department of Clinical Chemistry and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Pennacchi PC; Department of Clinical Chemistry and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Sandri S; Department of Clinical Chemistry and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Vicente AL; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
  • Scapulatempo-Neto C; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
  • Vazquez VL; Department of Pathology, Barretos Cancer Hospital, Barretos, Brazil.
  • Reis RM; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
  • Chauhan J; Department of Surgery Melanoma/Sarcoma, Barretos Cancer Hospital, Barretos, Brazil.
  • Goding CR; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
  • Smalley KS; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.
  • Maria-Engler SS; 3B's - PT Government Associate Laboratory, Braga/Guimarães, Guimarães, Portugal.
Oncogene ; 36(13): 1849-1861, 2017 03 30.
Article in En | MEDLINE | ID: mdl-27748762
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Drug Resistance, Neoplasm / Kruppel-Like Transcription Factors / Zinc Finger Protein GLI1 / Indoles / Melanoma / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Brasil Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Drug Resistance, Neoplasm / Kruppel-Like Transcription Factors / Zinc Finger Protein GLI1 / Indoles / Melanoma / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Brasil Country of publication: Reino Unido