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Optimization of the Ussing chamber setup with excised rat intestinal segments for dissolution/permeation experiments of poorly soluble drugs.
Forner, Kristin; Roos, Carl; Dahlgren, David; Kesisoglou, Filippos; Konerding, Moritz A; Mazur, Johanna; Lennernäs, Hans; Langguth, Peter.
Affiliation
  • Forner K; a Department of Pharmaceutical Technology and Biopharmaceutics , Johannes Gutenberg University , Mainz , Germany.
  • Roos C; b Department of Pharmacy , Uppsala University , Uppsala , Sweden.
  • Dahlgren D; b Department of Pharmacy , Uppsala University , Uppsala , Sweden.
  • Kesisoglou F; c Department of Biopharmaceutics, Pharmaceutical Sciences and Clinical Supply , Merck & Co. Inc ., Kenilworth , NJ , USA.
  • Konerding MA; d Institute of Clinical and Functional Anatomy , University Medical Center Johannes Gutenberg University , Mainz , Germany.
  • Mazur J; e Institute of Medical Biostatistics, Epidemiology and Informatics , University Medical Center Johannes Gutenberg University , Mainz , Germany.
  • Lennernäs H; b Department of Pharmacy , Uppsala University , Uppsala , Sweden.
  • Langguth P; a Department of Pharmaceutical Technology and Biopharmaceutics , Johannes Gutenberg University , Mainz , Germany.
Drug Dev Ind Pharm ; 43(2): 338-346, 2017 Feb.
Article in En | MEDLINE | ID: mdl-27762631
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solubility / Bile Acids and Salts / Cell Membrane Permeability / Caco-2 Cells / Intestines / Jejunum Limits: Animals / Humans Language: En Journal: Drug Dev Ind Pharm Year: 2017 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solubility / Bile Acids and Salts / Cell Membrane Permeability / Caco-2 Cells / Intestines / Jejunum Limits: Animals / Humans Language: En Journal: Drug Dev Ind Pharm Year: 2017 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido