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Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
Kato, Akihiko S; Burris, Kevin D; Gardinier, Kevin M; Gernert, Douglas L; Porter, Warren J; Reel, Jon; Ding, Chunjin; Tu, Yuan; Schober, Douglas A; Lee, Matthew R; Heinz, Beverly A; Fitch, Thomas E; Gleason, Scott D; Catlow, John T; Yu, Hong; Fitzjohn, Stephen M; Pasqui, Francesca; Wang, He; Qian, Yuewei; Sher, Emanuele; Zwart, Ruud; Wafford, Keith A; Rasmussen, Kurt; Ornstein, Paul L; Isaac, John T R; Nisenbaum, Eric S; Bredt, David S; Witkin, Jeffrey M.
Affiliation
  • Kato AS; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Burris KD; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Gardinier KM; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Gernert DL; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Porter WJ; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Reel J; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Ding C; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Tu Y; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Schober DA; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Lee MR; Applied Molecular Evolution, Eli Lilly and Company, San Diego, California, USA.
  • Heinz BA; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Fitch TE; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Gleason SD; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Catlow JT; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Yu H; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Fitzjohn SM; Lilly UK, Eli Lilly and Company, Windlesham, UK.
  • Pasqui F; Lilly UK, Eli Lilly and Company, Windlesham, UK.
  • Wang H; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Qian Y; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Sher E; Lilly UK, Eli Lilly and Company, Windlesham, UK.
  • Zwart R; Lilly UK, Eli Lilly and Company, Windlesham, UK.
  • Wafford KA; Lilly UK, Eli Lilly and Company, Windlesham, UK.
  • Rasmussen K; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Ornstein PL; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Isaac JT; Lilly UK, Eli Lilly and Company, Windlesham, UK.
  • Nisenbaum ES; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Bredt DS; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Witkin JM; Lilly Research Laboratory, Eli Lilly and Company, Indianapolis, Indiana, USA.
Nat Med ; 22(12): 1496-1501, 2016 12.
Article in En | MEDLINE | ID: mdl-27820603
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridones / Cerebellum / Prosencephalon / Receptors, AMPA / Epilepsy / Benzothiazoles / Anticonvulsants Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2016 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridones / Cerebellum / Prosencephalon / Receptors, AMPA / Epilepsy / Benzothiazoles / Anticonvulsants Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2016 Document type: Article Affiliation country: Estados Unidos