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Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.
Zetsche, Bernd; Heidenreich, Matthias; Mohanraju, Prarthana; Fedorova, Iana; Kneppers, Jeroen; DeGennaro, Ellen M; Winblad, Nerges; Choudhury, Sourav R; Abudayyeh, Omar O; Gootenberg, Jonathan S; Wu, Wen Y; Scott, David A; Severinov, Konstantin; van der Oost, John; Zhang, Feng.
Affiliation
  • Zetsche B; Broad Institute of MIT and Harvard, Cambridge, MA 02142.
  • Heidenreich M; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Mohanraju P; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Fedorova I; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Kneppers J; Department of Developmental Pathology, Institute of Pathology, Bonn Medical School, Sigmund Freud Street 25, 53127 Bonn, Germany.
  • DeGennaro EM; Broad Institute of MIT and Harvard, Cambridge, MA 02142.
  • Winblad N; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Choudhury SR; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Abudayyeh OO; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Gootenberg JS; Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, Stippeneng 4, 6708 WE Wageningen, Netherlands.
  • Wu WY; Broad Institute of MIT and Harvard, Cambridge, MA 02142.
  • Scott DA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Severinov K; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • van der Oost J; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Zhang F; Skolkovo Institute of Science and Technology, Skolkovo, 143025, Russia.
Nat Biotechnol ; 35(1): 31-34, 2017 Jan.
Article in En | MEDLINE | ID: mdl-27918548
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / RNA, Bacterial / Sequence Analysis, RNA / CRISPR-Associated Proteins / CRISPR-Cas Systems / Gene Editing Limits: Animals Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2017 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / RNA, Bacterial / Sequence Analysis, RNA / CRISPR-Associated Proteins / CRISPR-Cas Systems / Gene Editing Limits: Animals Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2017 Document type: Article Country of publication: Estados Unidos