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Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity.
Bhattacharyya, Sanchari; Bershtein, Shimon; Yan, Jin; Argun, Tijda; Gilson, Amy I; Trauger, Sunia A; Shakhnovich, Eugene I.
Affiliation
  • Bhattacharyya S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States.
  • Bershtein S; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
  • Yan J; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States.
  • Argun T; College of Chemical Engineering, Sichuan University, Chengdu, China.
  • Gilson AI; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States.
  • Trauger SA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, United States.
  • Shakhnovich EI; Small Molecule Mass Spectrometry, Northwest Laboratories, Harvard University, Cambridge, United States.
Elife ; 52016 12 10.
Article in En | MEDLINE | ID: mdl-27938662
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetrahydrofolate Dehydrogenase / Recombinant Proteins / Gene Dosage / Escherichia coli Proteins / Escherichia coli Language: En Journal: Elife Year: 2016 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetrahydrofolate Dehydrogenase / Recombinant Proteins / Gene Dosage / Escherichia coli Proteins / Escherichia coli Language: En Journal: Elife Year: 2016 Document type: Article Affiliation country: Estados Unidos