Successful treatment of refractory adult onset Still's disease with rituximab.
Reumatismo
; 68(3): 159-162, 2016 Dec 16.
Article
in En
| MEDLINE
| ID: mdl-27981819
ABSTRACT
Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition of unknown origin. In chronic disease, joint involvement is often predominant and erosions are noted in one third of patients. Therapeutic strategies derive from observational data. Corticosteroids are usually the first-line treatment. With inadequate response to corticosteroids, methotrexate appears the best choice to control disease activity and allow for tapering of steroid use. For refractory disease, biological therapy seems the most promising. We report here the case of a 38-year-old female patient with AOSD refractory to cytotoxic agents, treated by rituximab infusion therapy with favorable outcome.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Still's Disease, Adult-Onset
/
Antirheumatic Agents
/
Rituximab
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Reumatismo
Year:
2016
Document type:
Article