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Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor.
Flinspach, M; Xu, Q; Piekarz, A D; Fellows, R; Hagan, R; Gibbs, A; Liu, Y; Neff, R A; Freedman, J; Eckert, W A; Zhou, M; Bonesteel, R; Pennington, M W; Eddinger, K A; Yaksh, T L; Hunter, M; Swanson, R V; Wickenden, A D.
Affiliation
  • Flinspach M; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Xu Q; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Piekarz AD; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Fellows R; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Hagan R; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Gibbs A; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Liu Y; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Neff RA; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Freedman J; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Eckert WA; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Zhou M; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Bonesteel R; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Pennington MW; Peptides International, Louisville, KY 40299, USA.
  • Eddinger KA; University of California, San Diego, Department Anesthesiology and Pharmacology, 9500 Gilman Drive, La Jolla, CA 92093-0818, USA.
  • Yaksh TL; University of California, San Diego, Department Anesthesiology and Pharmacology, 9500 Gilman Drive, La Jolla, CA 92093-0818, USA.
  • Hunter M; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Swanson RV; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
  • Wickenden AD; Janssen R&D, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.
Sci Rep ; 7: 39662, 2017 01 03.
Article in En | MEDLINE | ID: mdl-28045073
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Spider Venoms / NAV1.7 Voltage-Gated Sodium Channel / Voltage-Gated Sodium Channel Blockers Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Spider Venoms / NAV1.7 Voltage-Gated Sodium Channel / Voltage-Gated Sodium Channel Blockers Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido