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A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II.
Sankarayanarayanan, Nehru Viji; Strebel, Tamara R; Boothello, Rio S; Sheerin, Kevin; Raghuraman, Arjun; Sallas, Florence; Mosier, Philip D; Watermeyer, Nicholas D; Oscarson, Stefan; Desai, Umesh R.
Affiliation
  • Sankarayanarayanan NV; Department of Medicinal Chemistry and Institute of Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA.
  • Strebel TR; Centre for Synthesis and Chemical Biology, University College of Dublin, Belfield, Dublin, 4, Ireland.
  • Boothello RS; Department of Medicinal Chemistry and Institute of Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA.
  • Sheerin K; Centre for Synthesis and Chemical Biology, University College of Dublin, Belfield, Dublin, 4, Ireland.
  • Raghuraman A; Department of Medicinal Chemistry and Institute of Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA.
  • Sallas F; Centre for Synthesis and Chemical Biology, University College of Dublin, Belfield, Dublin, 4, Ireland.
  • Mosier PD; Department of Medicinal Chemistry and Institute of Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA.
  • Watermeyer ND; Centre for Synthesis and Chemical Biology, University College of Dublin, Belfield, Dublin, 4, Ireland.
  • Oscarson S; Centre for Synthesis and Chemical Biology, University College of Dublin, Belfield, Dublin, 4, Ireland.
  • Desai UR; Department of Medicinal Chemistry and Institute of Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA, USA.
Angew Chem Int Ed Engl ; 56(9): 2312-2317, 2017 02 20.
Article in En | MEDLINE | ID: mdl-28124818
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin Cofactor II / Glucuronates / Heparitin Sulfate Type of study: Prognostic_studies Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Alemania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin Cofactor II / Glucuronates / Heparitin Sulfate Type of study: Prognostic_studies Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Alemania