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Direct Intracranial Injection of AAVrh8 Encoding Monkey ß-N-Acetylhexosaminidase Causes Neurotoxicity in the Primate Brain.
Golebiowski, Diane; van der Bom, Imramsjah M J; Kwon, Churl-Su; Miller, Andrew D; Petrosky, Keiko; Bradbury, Allison M; Maitland, Stacy; Kühn, Anna Luisa; Bishop, Nina; Curran, Elizabeth; Silva, Nilsa; GuhaSarkar, Dwijit; Westmoreland, Susan V; Martin, Douglas R; Gounis, Matthew J; Asaad, Wael F; Sena-Esteves, Miguel.
Affiliation
  • Golebiowski D; 1 Department of Neurology, University of Massachusetts Medical School , Worcester, Massachusetts.
  • van der Bom IMJ; 2 Horae Gene Therapy Center, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Kwon CS; 3 Department of Radiology, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Miller AD; 4 New England Center for Stroke Research, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Petrosky K; 5 Department of Neurosurgery, Massachusetts General Hospital , Boston, Massachusetts.
  • Bradbury AM; 6 New England Primate Research Center, Harvard Medical School , Southborough, Massachusetts.
  • Maitland S; 6 New England Primate Research Center, Harvard Medical School , Southborough, Massachusetts.
  • Kühn AL; 7 Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University , Alabama.
  • Bishop N; 8 Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University , Alabama.
  • Curran E; 1 Department of Neurology, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Silva N; 2 Horae Gene Therapy Center, University of Massachusetts Medical School , Worcester, Massachusetts.
  • GuhaSarkar D; 3 Department of Radiology, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Westmoreland SV; 4 New England Center for Stroke Research, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Martin DR; 9 Department of Animal Medicine, University of Massachusetts Medical School , Worcester, Massachusetts.
  • Gounis MJ; 6 New England Primate Research Center, Harvard Medical School , Southborough, Massachusetts.
  • Asaad WF; 6 New England Primate Research Center, Harvard Medical School , Southborough, Massachusetts.
  • Sena-Esteves M; 1 Department of Neurology, University of Massachusetts Medical School , Worcester, Massachusetts.
Hum Gene Ther ; 28(6): 510-522, 2017 06.
Article in En | MEDLINE | ID: mdl-28132521
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-N-Acetylhexosaminidases / Dependovirus / Gangliosidoses, GM2 / Dyskinesias / Genetic Vectors / Necrosis / Neurons Type of study: Etiology_studies Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2017 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-N-Acetylhexosaminidases / Dependovirus / Gangliosidoses, GM2 / Dyskinesias / Genetic Vectors / Necrosis / Neurons Type of study: Etiology_studies Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2017 Document type: Article Country of publication: Estados Unidos